CFRD Fact #13

April 4, 2008 at 7:07 am | In CFRD Facts, Cystic Fibrosis, Cystic Fibrosis Related Diabetes | 1 Comment
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Genotype is predictive of pancreatic status:

Delta F508 (the most common genetic defect in Cystic Fibrosis) homozygous genotype is associated with pancreatic insufficiency in nearly all patients.

This genotype is also at higher risk for CFRD.

CFRD Fact #8

March 19, 2008 at 7:16 am | In CFRD Facts, Cystic Fibrosis, Cystic Fibrosis Related Diabetes | Leave a Comment
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Interesting tidbits about CFRD:

Diabetic ketoacidosis (DKA) is rare. (I would love some more info on this).

Pancreatic insufficiency associated with CFRD.

A1c levels may underestimate abnormal glucose metabolism. (would love more info on this too). So far I have only found that there is an increased red cell turnover, causing a “diluted” A1c level.

The A1c level can show the average blood glucose levels over the past 2-3 months. A decent indicator of how well of control the diabetic has over their blood sugar levels.

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